Long-term Outcomes of CLIPPERS (Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids) in a Consecutive Series of 12 Patients

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Long-term outcomes of CLIPPERS (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) in a consecutive series of 12 patients.

BACKGROUND Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a central nervous system inflammatory disease. OBJECTIVE To describe the disease course of CLIPPERS. DESIGN A nationwide study was implemented to collect clinical, magnetic resonance imaging, cerebrospinal fluid, and brain biopsy specimen characteristics of patients with CL...

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clippers: chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids

a novel type of brainstem-predominant encephalomyelitis was first described as chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (clippers) in 2010 by pittocket al and then few additional patients were reported. here we report a 50-year-old iranian male who presented with a number of clinical features described as typical for clippers. the association...

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Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) with Limbic Encephalitis

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory central nervous system disorder that mainly involves in the brainstem, basal ganglia and cerebellum. We herein report the case of a patient with CLIPPERS, which was diagnosed based on the clinical and radiological features. After initially responded to steroid treatment, t...

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[CLIPPERS (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids)].

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) has been recently identified as an inflammatory central nervous system (CNS) disorder. Punctate and curvilinear gadolinium enhancement (peppering) the pons is a characteristic magnetic resonance imaging (MRI) feature of CLIPPERS. Pathogenesis of this disorder remains unknown. A specific seru...

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Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS)

1 Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA 2 Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA 3 Department of Neurology, Ghent University Hospital, Ghent, B.9000, Belgium 4 Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA 5 Department of Neurology, Mayo Clinic Co...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 2012

ISSN: 0003-9942

DOI: 10.1001/archneurol.2012.122